Description
There is a reason the Ruger Mark series has been the default answer to "what .22 pistol should I get" for decades. The Mark IV 22/45 takes that proven rimfire platform and builds it on a polymer grip frame shaped like a 1911, so the grip angle, thumb safety, and control layout will feel familiar the moment you pick it up. If you already run a 1911 or just prefer that steeper grip angle, this is the Mark IV to grab. This model, 40107, wears a blued 5.5 inch bull barrel that puts weight out front where it helps, settling the sights and soaking up what little recoil .22 LR produces.
Why the Mark IV 22/45 Shoots So Well
The cold hammer-forged bull barrel is threaded into a fixed tubular receiver, and the internal cylindrical bolt cycles inside it instead of a slide reciprocating on top. That means the sights never move relative to the bore, which is a big part of why these pistols have such a strong reputation for accuracy. The rear sight is adjustable, the front is a fixed ramp, and the receiver comes drilled and tapped so you can add a Weaver or Picatinny rail and mount a red dot when you are ready. Half-inch groups at 25 yards are well within reach with ammo this pistol likes.
One-Button Takedown, Zero Headaches
Anyone who owned an older Mark pistol remembers the reassembly puzzle. The Mark IV fixed all that. Press the recessed button at the back of the frame and the barrel-receiver assembly tilts up and lifts off, no tools needed. Slide the bolt out and you have full chamber-to-muzzle access for cleaning, which matters with a rimfire that eats bulk ammo by the brick.
A 22/45 That Earns Its Keep
At 34.4 ounces with a 9.75 inch overall length, it carries like a full-size pistol and shoots like a target gun. Two 10-round magazines are included, the manual safety is ambidextrous, and the aftermarket support for triggers, grips, and sights is enormous. Plinking, small game, new shooter training, bullseye practice, this one covers all of it.
Key Specifications
- Manufacturer Part Number: 40107
- UPC: 736676401079
- Model: Mark IV 22/45
- Caliber: .22 LR
- Capacity: 10+1
- Barrel Length: 5.5 in, bull profile
- Barrel Type: Cold hammer-forged
- Overall Length: 9.75 in
- Weight: 34.4 oz
- Finish: Blued
- Grip Frame: Polymer with checkered synthetic panels
- Sights: Fixed front, adjustable rear
- Receiver: Drilled and tapped for Weaver/Picatinny rail
- Safety: Ambidextrous manual
- Action: Semi-auto, single action
- Made In: Prescott, AZ, USA
What’s Included
- Ruger Mark IV 22/45 pistol
- Two 10-round magazines
- Owner's manual
- Factory box
Frequently Asked Questions
Can I mount a red dot on the Ruger Mark IV 22/45?
Yes, but you will need a rail first. The receiver comes drilled and tapped from the factory to accept a Weaver or Picatinny-style rail, which is sold separately. Once the rail is on, mounting a red dot or small pistol scope is quick, and the fixed barrel design means your zero stays put.
Will Mark III 22/45 magazines work in the Mark IV 22/45?
No, Mark III magazines are not compatible with the Mark IV. You will want to stick with Mark IV 22/45 magazines, and note that standard Mark IV mags and 22/45 mags also differ in their baseplates. The good news is this pistol ships with two 10-round magazines, and factory spares are easy to find.
How hard is the Mark IV 22/45 to take apart and clean?
This is the easiest Ruger Mark pistol to strip by a wide margin. Press the recessed button at the rear of the frame and the barrel and receiver assembly tilts up and lifts right off, no tools required. Pull the bolt out the back and you have straight-line access to clean from chamber to muzzle.
Is the bull barrel version heavy to shoot?
It weighs 34.4 ounces unloaded, roughly the same as a full-size 1911, and most of that weight sits forward in the barrel. That heft is a feature, not a drawback. It steadies your sight picture, tames muzzle movement, and makes this an exceptionally smooth pistol for target work and teaching new shooters.





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