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Ruger Mark IV 22/45 Lite .22 LR 4.4″ Black G10 Pistol (2x10rd)

UPC: 736676439591

$646.99

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Description

The 22/45 name tells you a lot about what this pistol is trying to do. The "22" is the caliber, the "45" is a nod to the 1911 grip angle it was designed to replicate. If you've spent any time behind a Government Model and then picked up a traditional Mark series pistol, you know the grip angle difference is jarring. Ruger fixed that with the 22/45 line, and the Lite version takes it a step further by swapping a heavy steel receiver for a ventilated aerospace-grade aluminum one, bringing the whole package down to a very manageable 25.9 ounces.

What Makes the Mark IV 22/45 Lite Different From Older Ruger .22s

Anyone who has owned a Mark II or Mark III knows the cleaning ritual. It was practically a rite of passage, and not a fun one. Ruger completely overhauled that with the Mark IV's one-button takedown system. Press the recessed button at the back of the frame, and the barrel-receiver assembly tilts up and off the grip frame with no tools required. You clean it from chamber to muzzle the correct way, and putting it back together doesn't require a YouTube tutorial. That alone was enough to win over a lot of longtime Ruger fans who had been putting off cleanings for years.

The barrel itself is cold hammer-forged stainless steel with a 1:16" right-hand twist and six grooves, tensioned inside the aluminum receiver for consistent sight-to-barrel alignment shot after shot. The internal cylindrical bolt design keeps that alignment locked in, which is a big part of why these pistols have always had a reputation for solid accuracy. Up top, you get a fixed front sight paired with a fully adjustable rear, plus a factory-installed Picatinny rail if you want to mount a red dot. The ambidextrous manual thumb safety also doubles as a magazine disconnect, and it can be converted to left-side only with the included washer if you prefer.

Grip, Feel, and the G10 Panels on This Model

This specific model (MPN 43959) comes with oversized G10 grip panels over a precision-molded polymer grip frame with a serrated frontstrap and checkered backstrap. The G10 gives you a secure, textured hold without being rough on your hands during a long range session. The grip angle feels right at home to anyone who trains regularly with a 1911-platform pistol, and the bolt stop sits right where a slide stop would on that same gun. Two factory 10-round magazines drop free via a left-side push-button release and are included in the box.

Key Specifications

  • Manufacturer Part Number (MPN): 43959
  • UPC: 736676439591
  • Caliber: .22 LR
  • Action: Single-Action Semi-Auto
  • Barrel Length: 4.4"
  • Barrel Style: Non-Threaded, Cold Hammer-Forged Stainless Steel
  • Rate of Twist: 1:16" RH, 6 Grooves
  • Overall Length: 8.40"
  • Height: 5.50"
  • Width: 1.52"
  • Weight: 25.9 oz.
  • Receiver Material: Aerospace-Grade Aluminum
  • Finish: Black Anodized
  • Grip Frame: Polymer with Oversized G10 Panels
  • Capacity: 10+1
  • Sights: Fixed Front, Fully Adjustable Rear
  • Safety: Ambidextrous Manual Thumb Safety with Magazine Disconnect

What’s Included

  • Ruger Mark IV 22/45 Lite pistol
  • Two 10-round magazines
  • Soft pistol case
  • Cable lock

Frequently Asked Questions

What does the "22/45" designation on the Mark IV actually mean?

The "22" refers to the .22 LR caliber, and the "45" is a direct reference to the 1911 .45 ACP pistol, specifically its grip angle and control layout. Ruger designed the 22/45 grip frame to replicate that familiar 1911 feel, which makes it especially popular for training and anyone who already shoots a 1911 platform. The magazine release is on the left side of the frame, just like a 1911, and the bolt stop sits right where the slide stop would be.

Is the barrel on the Mark IV 22/45 Lite (model 43959) threaded for a suppressor?

No, this specific model features a non-threaded barrel. The 4.4" cold hammer-forged stainless steel barrel on the 43959 does not have a muzzle thread. If suppressor compatibility is a priority, Ruger offers other Mark IV 22/45 Lite variants with a 1/2"-28 threaded barrel.

How hard is the Mark IV 22/45 Lite to clean compared to older Ruger .22 pistols?

Night and day difference. Previous Mark series pistols had a notoriously frustrating disassembly process that involved wrestling with an internal pivot pin and was a genuine headache even for experienced owners. The Mark IV uses a single recessed button at the rear of the frame that releases the barrel-receiver assembly to tilt right off the grip frame with no tools. Most people can figure it out the first time without any instructions, and reassembly is equally straightforward.

Can the ambidextrous safety on the Mark IV 22/45 Lite be converted to right-side only?

It works the other way around. The pistol ships with ambidextrous safety levers, and Ruger includes a washer that allows you to convert it to a left-side-only configuration if you find the right-side lever gets in the way during your grip. This is a practical feature for right-handed shooters who prefer a cleaner setup.

Does the Mark IV 22/45 Lite come with a red dot or optic already mounted?

No optic is included, but a factory-installed Picatinny rail runs along the top of the aluminum receiver, so it's ready for one right out of the box. It also ships with fully adjustable iron sights as a standard feature, so you're covered whether you run glass or stick with irons.

What kind of .22 LR ammo runs best in the Ruger Mark IV 22/45 Lite?

The Mark IV 22/45 Lite is generally not picky about rimfire ammo, and it has been reported to run reliably with standard-velocity loads from brands like CCI, Federal, and Winchester. High-velocity and hollow-point loads tend to cycle without issues as well. Like most .22 semi-autos, very low-velocity bulk ammo can occasionally cause light primer strikes or failures to cycle, so standard or high-velocity loads are the safe bet for consistent performance.

Additional information

UPC

736676439591

Manufacturer

Manufacturer Part Number

43959

Action

Barrel Finish

Black Anodized

Barrel Length

4.4"

Caliber/Gauge

.22 LR

Capacity

10 + 1

Color

Black

Model

Number of Magazines

2 10 rd.

Product Type

Semi-Auto Pistol

Safety

Ambidextrous

Shipping Weight

3.4

Sights

FS: Fixed | RS: Adjustable

Sights Type

Adjustable Sights

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