Description
The 378 Weatherby Magnum is about as serious as centerfire hunting ammunition gets. Designed to replace the legendary 375 Weatherby Magnum, this cartridge delivers deep penetration and the kind of bone-smashing power that's made it one of the world's most popular choices for trophy-class big game since 1955. Roy Weatherby's creation delivers 34 percent more muzzle energy than the already-powerful 375 H&H Magnum, making it an absolute sledgehammer in the field.
Weatheby loads this ammunition with a 270 grain Barnes TSX bullet, a 100 percent copper monolithic design that expands reliably and retains virtually all of its weight for maximum penetration. The TSX's four razor-sharp cutting petals expand to double the bullet diameter, creating extensive internal damage and devastating wound channels. This particular combination is engineered to generate high levels of shock trauma on game animals weighing up to 700 kilograms or more.
Weatherby Select Plus 378 Build Quality
Weatheby Select Plus ammunition uses only the finest components to match the precision of a handloader's best work. The massive case is loaded with high-grade premium powders paired with custom primers designed to handle the intense pressures this cartridge demands. Everything is assembled in Norma Precision brass with boxer-priming for reloading flexibility. The result is ammunition that delivers consistent velocity and exceptional accuracy round after round.
378 WBY Mag with Barnes TSX Performance
This load generates approximately 3060 fps from the muzzle, providing the flat trajectory and energy retention the 378 is known for. The Barnes TSX is velocity-friendly, expanding reliably from the high velocities the 378 produces, and it's one of the most consistent performers you can use on heavy game. Whether you're hunting African game, cape buffalo, or the largest North American elk and moose, this ammunition delivers the kind of reliable, repeatable performance that builds confidence in the field.
Key Specifications
- Caliber: 378 Weatherby Magnum
- Bullet Weight: 270 grains
- Bullet Type: Barnes TSX (100% copper monolithic)
- Muzzle Velocity: 3060 fps
- Case Material: Norma Precision Brass
- Primer: Federal 215 Magnum Rifle
- Powder: High-Grade Premium Powder
- Box Count: 20 rounds
- Manufacturer: Weatherby Inc.
- Manufacturer Part Number: B378270TSX
- UPC: 747115415854
What’s Included
- 20 rounds of 378 Weatherby Magnum ammunition
Frequently Asked Questions
What game animals is this 378 WBY Mag ammunition suitable for?
This load is designed for the largest and toughest game on Earth, including African dangerous game like Cape buffalo, as well as trophy elk, moose, and other heavy-bodied game. The 270 grain Barnes TSX is specifically selected to provide a balance between expansion and deep penetration on animals weighing several hundred pounds or more.
How does the Barnes TSX bullet perform at the 378's velocities?
The Barnes TSX excels in the 378 because it's engineered to expand reliably at high velocities. At around 3060 fps, the TSX opens aggressively and maintains nearly 100 percent weight retention, creating deep wound channels and maximum penetration. The bullet's design performs consistently across a wide range of impact distances and impact velocities typical of hunting situations.
Is this ammunition reloadable?
Yes. Weatherby Select Plus uses Norma Precision brass with boxer-priming, which allows for reloading. The high-quality brass is designed to withstand multiple reloading cycles, making it ideal for those who hand-load their own ammunition for this magnum cartridge.
What makes Weatherby Select Plus different from standard ammunition?
Weatherby Select Plus uses premium components throughout: Norma Precision brass, high-grade powders, and custom primers. The assembly process matches the precision of a dedicated hand-loader's work, resulting in consistent velocities and tight grouping from shot to shot. This attention to detail makes it reliable when the shot matters most.





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