Description
The 338-378 Weatherby Magnum is one of the most powerful cartridges available in factory ammunition. This is the ultimate choice for hunters who demand extreme velocity and energy from a premium 338 caliber load. Weatherby Select Plus pairs its proven magnum case design with Barnes' tipped TTSX projectile, a combination engineered specifically for extended-range accuracy and terminal performance.
What Makes Select Plus 338-378 Stand Out
This cartridge was originally developed in the 1960s as a wildcat, later reintroduced as a commercial Weatherby offering in 1998. It was designed to outperform the 338 Lapua with a larger case capacity and higher velocity potential. The 225-grain TTSX bullet rides on top of this velocity advantage, leaving the muzzle at 3,180 fps with muzzle energy of 5,052 foot-pounds. That's genuine magnum power in the factory-loaded form.
The Barnes TTSX Bullet Advantage
Barnes TTSX ammunition is engineered for lead-free performance without compromising results. The polymer-tipped bullet construction increases ballistic coefficient compared to the original TSX design, which translates to flatter trajectories and better long-range hold. Upon impact, the tip drives into the hollow point and initiates rapid expansion. The all-copper design creates four distinct cutting petals that produce massive wound channels while the bullet core remains intact, delivering consistent penetration through heavy bone and thick muscle. This controlled expansion is what makes Barnes bullets a trusted choice for serious hunting applications.
Key Specifications
- Manufacturer: Weatherby
- Caliber: .338-378 Weatherby Magnum
- Bullet Weight: 225 grains
- Bullet Type: Barnes Tipped TSX (lead-free, solid copper)
- Muzzle Velocity: 3,180 fps
- Muzzle Energy: 5,052 ft-lbs
- Ballistic Coefficient: .514
- Case Material: Brass, reloadable
- Primer Type: Magnum Rifle
- Units Per Box: 20 rounds
- Manufacturer Part Number: B333225TTSX
- UPC: 747115425129
What’s Included
- 20 rounds of factory-loaded 338-378 Weatherby Magnum ammunition
Frequently Asked Questions
What is the effective range of this 338-378 Weatherby Magnum ammunition?
The 338-378 Weatherby Magnum is designed for extreme long-range performance. With a muzzle velocity of 3,180 fps and ballistic coefficient of .514, this load maintains velocity well beyond typical big game hunting distances. Real-world effective range depends on your rifle setup, optics, and proficiency, but many shooters successfully take game well beyond 500 yards with this cartridge.
Is this ammunition reloadable?
Yes, the brass cases are reloadable. The Select Plus line uses quality Weatherby brass that can be reloaded multiple times with proper care and equipment. This makes the 338-378 Magnum more economical for shooters who reload, though components like magnum rifle primers and slow-burning powders are required.
How does the Barnes TTSX bullet perform compared to traditional lead-core bullets?
Barnes TTSX ammunition is engineered to expand reliably and penetrate deeply while remaining lead-free. The solid copper construction and polymer tip deliver consistent terminal performance with quick, humane expansion. Many hunters prefer TTSX ammunition for its accuracy potential and proven results on large game, though it typically requires slightly less gun range than softer lead-core alternatives.
Will this ammo work in any 338-378 Weatherby rifle?
This ammunition is loaded to factory specifications and will work in any rifle properly chambered for the 338-378 Weatherby Magnum. Always verify your rifle's chamber and run a few rounds over a chronograph to confirm velocity consistency before relying on it for hunting.



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